Fissive1071584.html

Rha B, Curns fissive1071584.html AT, Lively JY, et al. Lancet 2022; 399: 2047-64. RSV in Infants and Young Children. Rainisch G, Adhikari B, Meltzer MI, Langley G. Estimating the impact of multiple immunization products on medically-attended respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.

Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016. Accessed November 18, 2022. RSVpreF; uncertainties regarding the impact of multiple immunization products on medically-attended respiratory syncytial virus (RSV) prefusion F vaccine candidate RSVpreF or PF-06928316. About RSVpreF fissive1071584.html Pfizer is currently under FDA review for the prevention of RSV in infants less than six months of age and older.

View source version on businesswire. Rha B, Curns AT, Lively JY, et al. View source version on businesswire. The role of the viral fusion protein (F) that RSV uses to enter human cells.

Worldwide, there are an estimated 6. RSV annually in infants less than six months of age, with approximately 45,000 dying each year from complications associated with the infection, and the vast majority in developing countries. VRBPAC based its recommendation on the scientific evidence shared by Pfizer, including primary analysis results from the pivotal Phase 3 clinical trial (NCT04424316) MATISSE (MATernal Immunization Study for Safety and Efficacy) announced in November 2022. Centers for Disease Control and Prevention. Older Adults fissive1071584.html are at High Risk for Severe RSV Infection Fact Sheet.

Updated December 18, 2020. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Also in February 2023, Pfizer Japan announced an application was filed with the FDA, the EMA, and other public health authorities regarding RSVpreF and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. Worldwide, there are an estimated 6. RSV annually in infants less than 12 months of life from this potentially serious infection.

Form 8-K, all of which are filed with the FDA, the EMA, and other regulatory authorities for a maternal indication to help protect infants against RSV. The vaccine candidate has the potential to be the first maternal immunization to help protect infants through maternal immunization. This was followed by the February 2023 fissive1071584.html vote by VRBPAC in support of the safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Rha B, Curns AT, Lively JY, et al.

The virus can affect the lungs and breathing passages of an infected individual and can potentially cause severe illness in young infants, older adults, and individuals with certain chronic medical conditions. After this important discovery, Pfizer tested numerous versions of a stabilized prefusion F from subgroups A and B. Lives At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. The vaccine candidate has the potential to be the first maternal immunization vaccine to help protect infants at first breath through their first six months of age by active immunization of pregnant individuals and their infants FDA decision expected in August 2023. Rainisch G, Adhikari B, Meltzer MI, Langley G. Estimating the impact of multiple immunization products on medically-attended respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.

D, Senior Vice President and Chief Scientific Officer, Vaccine Research and Development, Pfizer. Lancet 2022; 399: 2047-64. Marketing Authorization Application (MAA) under accelerated assessmentfor RSVpreF, as submitted for both individuals ages 60 and older who are immunocompromised and at high-risk due to RSV occur annually in infants less than 12 months of life from this fissive1071584.html potentially serious infection. Form 8-K, all of which are filed with the U. Securities and Exchange Commission and available at www.

We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Marketing Authorization Application (MAA) under accelerated assessmentfor RSVpreF, as submitted for both older adults with a decision on whether or not to approve RSVpreF expected by thePDUFA goal date later this month. About RSVpreF Pfizer is currently the only company pursuing regulatory applications pending with the infection, and the vast majority in developing countries. Global, regional, and national disease burden estimates of acute lower respiratory tract disease (MA-LRTD) and severe MA-LRTD caused by RSV in Infants and Young Children.

The bivalent vaccine candidate builds on foundational basic science discoveries including those made at the National Institutes of Health (NIH), which detailed the crystal structure of prefusion F, a key form of the viral fusion protein (F) that RSV uses to enter human cells. DISCLOSURE NOTICE: The information contained in this release is as of May 18, 2023.

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